Title: Comparison of Cytochrome P4501A Induction in Blood and Liver Cells of Sea Otters
Project Year and Number: 2001: 01534
Other Fiscal Years and Numbers for this Project: None
Principal Investigator (PI): Brenda Ballachey, DOI
Research Location: Prince William Sound
Restoration Category: Research
Injured Resources Addressed: Sea Otters
Abstract: This project will sample livers from the sea otters captured under Project /423 for assays of CYP1A and for examination of histopathological changes. Liver CYP1A levels will be compared to those measured in blood from the same individuals. The project will also assay for CYP1A in archived frozen liver samples from sea otters that were oiled and died in 1989, to enable comparison of current levels of CYP1A induction with levels in sea otters that had a known high degree of oil exposure. The results of this project will provide a basis for comparison of cytochrome P4501A induction in sea otters in 1989, in 1996-98, and in 2001, and will help determine if there is a decline in CYP1A levels over time.
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Proposal: View PDF (116 KB)
Funding Recommendations: View
Funding Detail For: 2001
Quarterly Project Tasks For: 2001
Annual Report: 2001: Not Available
Final Report: View
Publications from this Project: None Available